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PMID: 4873064 Published · ppublish English Journal Article

Escherichia coli: high resistance or dependence on streptomycin produced by the same allele.

Science (New York, N.Y.) ·Vol. 161 ·No. 3840 ·1968-08-02 ·Pages 478-9

Luzzatto L, Schlessinger D, Apirion D

Abstract

Mutations to streptomycin resistance in Escherichia coli K12, when transferred to a C strain, can confer dependence on streptomycin. These alternatives in expression of the allele are probably a result of interaction between two ribosomal proteins.

MeSH Terms
Alleles Bacterial Proteins/metabolism Drug Resistance, Microbial Escherichia coli/metabolism Genetics, Microbial Mutation Pharmacogenetics Recombination, Genetic Ribosomes/metabolism Streptomycin/pharmacology Transduction, Genetic
Chemicals
Bacterial Proteins Streptomycin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Luzzatto L
Schlessinger D
Apirion D
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1968-08-02
Pages
478-9
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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