Phosphorylation and inactivation of aminoglycosidic antibiotics by E. coli carrying R factor.

Adenosine Triphosphate/pharmacology Alkaline Phosphatase/metabolism Anti-Bacterial Agents/metabolism,pharmacology Culture Media Drug Resistance, Microbial Escherichia coli/drug effects,enzymology,metabolism Kanamycin/metabolism Magnesium Neomycin/metabolism Paromomycin/metabolism Phosphates/metabolism Shigella sonnei/drug effects Streptomycin/metabolism

Anti-Bacterial Agents Culture Media Phosphates Kanamycin Paromomycin Adenosine Triphosphate Alkaline Phosphatase Neomycin Magnesium Streptomycin