Hu-1: Major histocompatibility locus in man.

Science (New York, N.Y.) ·Vol. 156 ·No. 3781 ·1967-06-16 ·Pages 1506-8

Bach FH, Amos DB

Abstract

A single locus with 15 or more alleles controls reactivity in mixed leukocyte culture tests. Genes at this locus also control most of the specificities measured by cytotoxic antiserums to leukocytes. Both of these tests can be used to predict survival of skin grafts. It is proposed that this is the major histocompatibility locus in man.

MeSH Terms

Antigens Culture Techniques Genes Genetics, Medical Histocompatibility Humans Leukocytes/immunology Skin Transplantation Transplantation Immunology

Chemicals

Antigens

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Bach F H

Amos D B

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.156.3781.1506

Published

1967-06-16

Pages

1506-8

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.156.3781.1506 View journal details

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