Resistant urinary infections resulting from changes in resistance pattern of faecal flora induced by sulphonamide and hospital environment.

British medical journal ·Vol. 3 ·No. 5718 ·1970-08-08 ·Pages 305-9

Lincoln K, Lidin-Janson G, Winberg J

Abstract

The faecal flora was studied in eight children admitted to hospital for treatment of a first urinary infection with sulphonamides. The original, sulphonamide-sensitive Escherichia coli organisms were found to disappear, to be replaced by other E. coli serotypes that were almost invariably resistant to sulphonamides. Some of these serotypes carried R-factors for multiple antibiotic resistance.Possibly some urinary infections with antibiotic-resistant organisms may be due to faecal organisms whose resistance has been changed by previous antibiotic treatment. Hence it is important to study the effects of individual antibiotics on the faecal flora.

MeSH Terms

Drug Resistance, Microbial Escherichia coli/drug effects Feces/microbiology Female Hospitals Humans Infant Male Serotyping Sulfonamides/therapeutic use Urinary Tract Infections/etiology,microbiology Urine/microbiology

Chemicals

Sulfonamides

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Lincoln K

Lidin-Janson G

Winberg J

References (13)

13 references, click to expand

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J Urol. 1968 May;99(5):632-8 PMID: 4869868
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Bacteriol Rev. 1968 Mar;32(1):55-83 PMID: 4869941
Transferable drug resistance and other transferable agents in strains of Escherichia coli from two human populations.
Lancet. 1968 Jun 29;1(7557):1389-93 PMID: 4172987
Studies of urinary tract infections in infancy and childhood. X. Short or long-term treatment in girls with first or second-time urinary tract infections uncomplicated by obstructive urological abnormalities.
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Br Med J. 1969 Apr 19;2(5650):145-6 PMID: 4888353
Urinary tract infections: correlation between organisms obtained simultaneously from the urine and feces of patients with bacteriuria and pyuria.
J Urol. 1969 May;101(5):765-7 PMID: 4976354
The epidemiology of nonenteric Escherichia coli infections: prevalence of serological groups.
J Clin Invest. 1962 Sep;41:1760-5 PMID: 13923136
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Bacteriol Rev. 1963 Mar;27:87-115 PMID: 13999115
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Article Info

Journal

British medical journal

Abbr.

Br Med J

ISSN

0007-1447

DOI

10.1136/bmj.3.5718.305

Published

1970-08-08

Pages

305-9

Language

English

Region

England

NLM ID

0372673

PMCID

PMC1701508

Subset

External Links

PubMed source DOI: 10.1136/bmj.3.5718.305 PMC Full Text

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Resistant urinary infections resulting from changes in resistance pattern of faecal flora induced by sulphonamide and hospital environment.

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