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PMID: 4924307 Published · ppublish ger Journal Article

[Effects of the intravenous infusion of nicotinic acid on blood concentrations of substrates, metabolites and hormones in juvenile-onset diabetes].

Effekte der intravenösen Nikotinsäureinfusion auf Substrat-, Metabolit- und Hormonkonzentrationen im Blut beim juvenil-manifestierten Diabetes mellitus.

Diabetologia ·Vol. 6 ·No. 6 ·1970-12-00 ·Pages 550-7

Michaelis D, Hahn HJ, Michael R, Schäfer H, Knospe S, Jutzi E, Wulfert P

Abstract

暂无摘要

MeSH Terms
17-Hydroxycorticosteroids/blood Animals Blood Glucose/analysis Carbon Isotopes Catecholamines/blood Diabetes Mellitus/blood,diagnosis,metabolism Diabetes Mellitus, Type 1/blood,diagnosis,metabolism Diagnosis, Differential Fatty Acids, Nonesterified/blood Glycerol/blood Humans In Vitro Techniques Insulin/blood,metabolism Insulin Secretion Iodine Isotopes Islets of Langerhans/metabolism Lactates/blood Mice Nicotinic Acids/pharmacology Pyruvates/blood
Chemicals
17-Hydroxycorticosteroids Blood Glucose Carbon Isotopes Catecholamines Fatty Acids, Nonesterified Insulin Iodine Isotopes Lactates Nicotinic Acids Pyruvates Glycerol
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Michaelis D
Hahn H J
Michael R
Schäfer H
Knospe S
Jutzi E
Wulfert P
References (33)
33 references, click to expand
  1. The effect of nicotinic acid on the plasma free fatty acid; demonstration of a metabolic type of sympathicolysis.
    Acta Med Scand. 1962 Dec;172:641-5 PMID: 14018702
  2. OBSERVATIONS ON THE ETIOLOGY AND THERAPY OF "BRITTLE" DIABETES.
    Can Med Assoc J. 1964 Apr 18;90:953-9 PMID: 14139995
  3. The effect of nicotinic acid on adipose tissue metabolism in vitro.
    Metabolism. 1965 Jul;14(7):836-40 PMID: 25286474
  4. Dynamics of insulin secretion by the perfused rat pancreas.
    Endocrinology. 1968 Sep;83(3):572-84 PMID: 4877098
  5. THE COLORIMETRIC MICRO-DETERMINATION OF NON-ESTERIFIED FATTY ACIDS IN PLASMA.
    Clin Chim Acta. 1964 Feb;9:122-5 PMID: 14122498
  6. Plasma-insulin activity in diabetes mellitus measured by the rat diaphragm technique.
    Lancet. 1955 Sep 17;269(6890):583-7 PMID: 13252925
  7. [A new determination of the neutral fats in blood serum and tissue. I. Principles, procedure, and discussion of the method].
    Klin Wochenschr. 1966 Mar 1;44(5):262-7 PMID: 5983837
  8. A possible role for the adenylcyclase system in insulin secretion.
    J Clin Invest. 1967 Nov;46(11):1724-34 PMID: 4294054
  9. Biphasic nature of blood glucose and free fatty acid changes following intravenous nicotinic acid in man.
    J Clin Endocrinol Metab. 1967 Mar;27(3):440-3 PMID: 6023585
  10. [A new determination of the neutral fats in blood serum and tissue. II. Reliability of the method, other neutral fat determinations, normal values for triglycerides and glycerin in human blood].
    Klin Wochenschr. 1966 Mar 1;44(5):267-73 PMID: 5983838
  11. Protein measurement with the Folin phenol reagent.
    J Biol Chem. 1951 Nov;193(1):265-75 PMID: 14907713
  12. A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines.
    J Pharmacol Exp Ther. 1962 Dec;138:360-75 PMID: 14013351
  13. Studies on the action of insulin in isolated adipose tissue cells. I. Stimulation of incorporation of 32P-labeled inorganic phosphate into mononucleotides in the absence of glucose.
    J Biol Chem. 1968 Aug 10;243(15):4020-6 PMID: 4299100
  14. Metabolic effects of nicotinic acid in acute insulin deficiency in the rat.
    Diabetes. 1968 Jun;17(6):353-61 PMID: 4968071
  15. [Studies on the effect of nicotinic acid on stimulated lipolysis].
    Z Klin Chem Klin Biochem. 1968 Nov;6(6):497-8 PMID: 4301965
  16. Effect of a single dose of nicotinic acid on plasma lipids in patients with hyperlipoproteinemia.
    Acta Med Scand. 1968 May;183(5):457-65 PMID: 4883477
  17. Juvenile diabetes mellitus, a deficiency in insulin.
    Diabetes. 1968 Jan;17(1):27-32 PMID: 4952859
  18. Effects of lipolytic and antilipolytic substances on adenosine 3',5'-monophosphate levels in isolated fat cells.
    J Biol Chem. 1968 Apr 25;243(8):1705-12 PMID: 4384670
  19. IN VITRO INHIBITION OF THE FAT-MOBILIZING ACTION OF NOREPINEPHRINE.
    Proc Soc Exp Biol Med. 1963 Dec;114:599-600 PMID: 14115265
  20. Insulin secretion from toadfish islet tissue stimulated by pyridine nucleotides.
    Science. 1968 Oct 11;162(3850):283-4 PMID: 4386347
  21. 3-Pyridineacetic acid and nicotinic acid: blood levels, urinary elimination and excretion of nicotinic acid derivatives in man.
    Nature. 1962 Mar 10;193:948-9 PMID: 13898750
  22. The plasma free fatty acid rebound induced by nicotinic acid.
    J Lipid Res. 1967 May;8(3):239-44 PMID: 6038564
  23. Insulin secretion and the intracellular concentrations of glucose 6-phosphate and 6-phosphogluconate in isolated islets of Langerhans.
    Biochem J. 1968 Sep;109(3):30P-31P PMID: 4879530
  24. Effect of dibutyryl-3',5'-AMP, theophylline and norepinephrine on lipolytic action of growth hormone and glucocorticoid in white fat cells.
    Endocrinology. 1968 Apr;82(4):825-30 PMID: 4316222
  25. MEASUREMENT OF SMALL QUANTITIES OF INSULIN-LIKE ACTIVITY USING RAT ADIPOSE TISSUE. II. EVALUATION OF PERFORMANCE.
    J Clin Invest. 1960 Sep;39(9):1499-510 PMID: 16695833
  26. THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.
    Biochem J. 1963 Oct;89:114-23 PMID: 14097352
  27. INHIBITION OF THE MOBILIZATION OF FREE FATTY ACIDS FROM ADIPOSE TISSUE IN DIABETES. II. EFFECT OF NICOTINIC ACID AND ACETYLSALICYLATE ON BLOOD GLUCOSE IN HUMAN DIABETICS.
    Acta Med Scand. 1965 Jul;178:71-9 PMID: 14317335
  28. Pathologic anatomy of the pancreas in juvenile diabetes mellitus.
    Diabetes. 1965 Oct;14(10):619-33 PMID: 5318831
  29. Immunoassay of insulin with insulin-antibody precipitate.
    Biochem J. 1963 Jul;88:137-46 PMID: 13952078
  30. [On the metabolite content and the metabolite concentration in the liver of the rat].
    Biochem Z. 1959;332:18-46 PMID: 14402528
  31. Inhibition of the mobilization of free fatty acids from adipose tissue. Physiological aspects on the mechanisms for the inhibition of mobilization of FFA from adipose tissue.
    Ann N Y Acad Sci. 1965 Oct 8;131(1):119-42 PMID: 5323923
  32. Secretion of insulin induced by amino acids and glucose in diabetes mellitus.
    J Clin Endocrinol Metab. 1968 Feb;28(2):266-76 PMID: 4865756
  33. [The effect of nicotinic acid and propranolol on the lipolytic action of catecholamines and peptide hormones in vitro].
    Z Gesamte Exp Med. 1967;143(1):79-84 PMID: 4297519
Article Info
Journal
Diabetologia
Abbr.
Diabetologia
ISSN
0012-186X
DOI
10.1007/BF00418220
Published
1970-12-00
Pages
550-7
Language
ger
Region
Germany
NLM ID
0006777
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00418220 View journal details
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