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PMID: 4929914 Published · ppublish English Journal Article

Lead suppression of mouse resistance to Salmonella typhimurium.

Science (New York, N.Y.) ·Vol. 172 ·No. 3987 ·1971-06-04 ·Pages 1031-2

Hemphill FE, Kaeberle ML, Buck WB

Abstract

Mice were treated with subclinical doses of lead nitrate for 30 days. Lead-treated mice showed greater susceptibility to challenge with Salmonella typhimurium than controls which received no lead. This result confirms the hypothesis that treatment with lead reduces the resistance of mice to bacterial infection.

MeSH Terms
Animals Lead/pharmacology,toxicity Mice Salmonella Infections, Animal/immunology,mortality Salmonella typhimurium/immunology
Chemicals
Lead
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hemphill F E
Kaeberle M L
Buck W B
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.172.3987.1031
Published
1971-06-04
Pages
1031-2
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.172.3987.1031 View journal details
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