Effects of macrolide antibiotics on the ribosomal peptidyl transferase in cell-free systems derived from Escherichia coli B and erythromycin-resistant muytant of Escherichia coli B.

Anti-Bacterial Agents/pharmacology Carbon Isotopes Chloramphenicol/pharmacology Depression, Chemical Drug Antagonism Drug Resistance, Microbial Erythromycin/pharmacology Escherichia coli/drug effects,growth & development,metabolism Genetics, Microbial Hybridization, Genetic Kinetics Leucomycins/antagonists & inhibitors,pharmacology Lysine/metabolism Mutation Oleandomycin/pharmacology Peptide Biosynthesis Peptide Chain Elongation, Translational Phenylalanine/metabolism Polynucleotides/metabolism Puromycin/metabolism RNA, Transfer/metabolism Ribosomes/drug effects,metabolism Stimulation, Chemical

Anti-Bacterial Agents Carbon Isotopes Leucomycins Polynucleotides Phenylalanine Puromycin Erythromycin Chloramphenicol RNA, Transfer Lysine Oleandomycin