Biological ion exchanger resins. II. QUERP water and ion exchange selectivity.

Biophysical journal ·Vol. 11 ·No. 9 ·1971-09-00 ·Pages 761-72

Damadian R, Goldsmith M, Zaner KS

Abstract

Biological selectivity is shown to vary with medium osmotic strength and temperature. Selectivity reversals occur at 4 degrees C and at an external osmolality of 0.800 indicating that intracellular hydration and endosolvent (intracellular water) structure are important determinants in selectivity. Magnetic resonance measurements of line width by steady-state nuclear magnetic resonance (NMR) indicate a difference in the intracellular water signal of 16 Hz between the K form and Na form of Escherichia coli, providing additional evidence that changes in the ionic composition of cells are accompanied by changes in endosolvent structure. The changes were found to be consistent with the thermodynamic and magnetic resonance properties of aqueous electrolyte solutions. Calculation of the dependence of ion-pairing forces on medium dielectric reinforces the role of endosolvent structure in determining ion exchange selectivity.

MeSH Terms

Biological Transport Cesium Chlorides Dialysis Escherichia coli/metabolism Ion Exchange Ion Exchange Resins Lithium Magnetic Resonance Spectroscopy Mathematics Osmolar Concentration Potassium Potassium Chloride/metabolism Rubidium Sodium Sodium Chloride/metabolism Sucrose Temperature Thermodynamics Tromethamine

Chemicals

Chlorides Ion Exchange Resins Tromethamine Cesium Sodium Chloride Sucrose Potassium Chloride Lithium Sodium Rubidium Potassium

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Damadian R

Goldsmith M

Zaner K S

References (7)

7 references, click to expand

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J Bacteriol. 1960 Jul;80:21-4 PMID: 14428935
Nuclear magnetic resonance evidence using D2O for structured water in muscle and brain.
Biophys J. 1969 Mar;9(3):303-19 PMID: 5780710
Thermodynamic properties of ion exchange resins; free energy of swelling as related to ion selectivities.
Ann N Y Acad Sci. 1953 Nov 11;57(3):87-104 PMID: 13139310
Evidence for the existence of a minimum of two phases of ordered water in skeletal muscle.
Nature. 1969 May 24;222(5195):747-50 PMID: 5786190
Ion metabolism in a potassium accumulation mutant of Escherichia coli B. I. Potassium metabolism.
J Bacteriol. 1968 Jan;95(1):113-22 PMID: 4866095
Growth and Fermentation of Bacteria Near Their Minimum Temperature.
J Bacteriol. 1936 Nov;32(5):485-97 PMID: 16559967
Biological ion exchanger resins. I. Quantitative electrostatic correspondence of fixed charge and mobile counter ion.
Biophys J. 1971 Sep;11(9):739-60 PMID: 4943652

Article Info

Journal

Biophysical journal

Abbr.

Biophys J

ISSN

0006-3495

DOI

10.1016/S0006-3495(71)86252-5

Published

1971-09-00

Pages

761-72

Language

English

Region

United States

NLM ID

0370626

PMCID

PMC1484048

Subset

External Links

PubMed source DOI: 10.1016/S0006-3495(71)86252-5 PMC Full Text View journal details

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Biological ion exchanger resins. II. QUERP water and ion exchange selectivity.

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