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PMID: 4947213 Published · ppublish English Journal Article

Meningococcal infections. 5. Duration of polysaccharide-vaccine-induced antibody.

Bulletin of the World Health Organization ·Vol. 45 ·No. 3 ·1971-00-00 ·Pages 291-3

Artenstein MS

Abstract

Serum antibodies induced in 12 volunteer subjects by injection of group A and group C meningococcal polysaccharide vaccines were found to persist for periods exceeding 14 months. Antibody response was measured by indirect haemagglutination and fluorescent antibody assays. Peak titres were reached in 2-8 weeks.

MeSH Terms
Antibody Formation Bacterial Vaccines Fluorescent Antibody Technique Hemagglutination Tests Humans Meningococcal Infections/immunology Polysaccharides, Bacterial Time Factors Vaccination
Chemicals
Bacterial Vaccines Polysaccharides, Bacterial
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Artenstein M S
References (7)
7 references, click to expand
  1. ANTIBODY FORMATION IN VOLUNTEERS FOLLOWING INJECTION OF PNEUMOCOCCI OR THEIR TYPE-SPECIFIC POLYSACCHARIDES.
    J Exp Med. 1946 Mar 31;83(4):303-20 PMID: 19871532
  2. Human immunity to the meningococcus. 3. Preparation and immunochemical properties of the group A, group B, and group C meningococcal polysaccharides.
    J Exp Med. 1969 Jun 1;129(6):1349-65 PMID: 4977282
  3. Human immunity to the meningococcus. I. The role of humoral antibodies.
    J Exp Med. 1969 Jun 1;129(6):1307-26 PMID: 4977280
  4. Human immunity to the meningococcus. IV. Immunogenicity of group A and group C meningococcal polysaccharides in human volunteers.
    J Exp Med. 1969 Jun 1;129(6):1367-84 PMID: 4977283
  5. The relationship between group A and group C meningococcal polysaccharides and serum opsonins in man.
    J Exp Med. 1970 Mar 1;131(3):499-513 PMID: 4189835
  6. Human immunity to the meningococcus. II. Development of natural immunity.
    J Exp Med. 1969 Jun 1;129(6):1327-48 PMID: 4977281
  7. Cutaneous reactions and antibody response to meningococcal group C polysaccharide vaccines in man.
    J Infect Dis. 1970 Apr;121(4):372-7 PMID: 4985950
Article Info
Journal
Bulletin of the World Health Organization
Abbr.
Bull World Health Organ
ISSN
0042-9686
Published
1971-00-00
Pages
291-3
Language
English
Region
Switzerland
NLM ID
7507052
PMCID
PMC2427925
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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