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PMID: 497175 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Activation of vinyl chloride to covalently bound metabolites: roles of 2-chloroethylene oxide and 2-chloroacetaldehyde.

Biochemistry ·Vol. 18 ·No. 23 ·1979-11-13 ·Pages 5177-82

Guengerich FP, Crawford WM, Watanabe PG

Abstract

暂无摘要

MeSH Terms

Acetaldehyde/analogs & derivatives,metabolism Alcohol Oxidoreductases/metabolism Animals Cytochrome P-450 Enzyme System/metabolism Epoxide Hydrolases/metabolism Ethylene Oxide/metabolism Kinetics Male Microsomes, Liver/drug effects,metabolism Phenobarbital/pharmacology Rats Vinyl Chloride/metabolism Vinyl Compounds/metabolism

Chemicals

Vinyl Compounds chloroethylene oxide Cytochrome P-450 Enzyme System chloroacetaldehyde Alcohol Oxidoreductases Epoxide Hydrolases Acetaldehyde Ethylene Oxide Vinyl Chloride Phenobarbital

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Guengerich F P

Crawford W M

Watanabe P G

Article Info

Journal

Biochemistry

Abbr.

Biochemistry

ISSN

0006-2960

DOI

10.1021/bi00590a023

Published

1979-11-13

Pages

5177-82

Language

English

Region

United States

NLM ID

0370623

Subset

External Links

PubMed source DOI: 10.1021/bi00590a023 View journal details

Analysis Services

Activation of vinyl chloride to covalently bound metabolites: roles of 2-chloroethylene oxide and 2-chloroacetaldehyde.

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