L-tyrosine-3,5-3H assay for tyrosinase development in skin of newborn hamsters.

Science (New York, N.Y.) ·Vol. 164 ·No. 3881 ·1969-05-16 ·Pages 838-9

Pomerantz SH

Abstract

Tyrosinase in hamster skin, measured by the production of (3)HOH from L-tyrosine-3,5-(3)H, increases about sevenfold in specific activity from the 14-day fetus to day 6 of life. Albino hamsters exhibit no activity, but enzyme is present in the ventral (white) areas of the Syrian hamster. 3,4-Dihydroxy-L-phenylalanine is required as a cosubstrate.

MeSH Terms

Aging Animals Animals, Newborn Catechol Oxidase/analysis,metabolism Cricetinae Fetus Skin/enzymology Tritium Tyrosine/metabolism

Chemicals

Tritium Tyrosine Catechol Oxidase

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Pomerantz S H

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.164.3881.838

Published

1969-05-16

Pages

838-9

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.164.3881.838 View journal details

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L-tyrosine-3,5-3H assay for tyrosinase development in skin of newborn hamsters.

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