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PMID: 4978752 Published · ppublish English Journal Article

Hepatitis in marmosets: induction of disease with coded specimens from a human volunteer study.

Science (New York, N.Y.) ·Vol. 165 ·No. 3895 ·1969-08-22 ·Pages 816-7

Holmes AW, Wolfe L, Rosenblate H, Deinhardt F

Abstract

Marmosets inoculated with plasma from three early acute hepatitis patients developed hepatitis 30 to 40 days later. Other groups of marmosets receiving preinfection plasmas from the same patients showed no evidence of hepatitis in this experiment. It is, therefore, most probable that hepatitis in marmosets represented transmission of human disease rather than activation of latent "marmoset hepatitis."

MeSH Terms
Animals Aspartate Aminotransferases/blood Disease Vectors Haplorhini Hepatitis A/blood,etiology Hepatitis, Animal/etiology Humans Isocitrate Dehydrogenase/blood Liver/pathology
Chemicals
Isocitrate Dehydrogenase Aspartate Aminotransferases
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Holmes A W
Wolfe L
Rosenblate H
Deinhardt F
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1969-08-22
Pages
816-7
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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