Hereditary deficiency of the second component of complement (C2) in man: correlation of C2 haemolytic activity with immunochemical measurements of C2 protein.

Immunology ·Vol. 18 ·No. 6 ·1970-06-00 ·Pages 943-54

Ruddy S, Klemperer MR, Rosen FS, Austen KF, Kumate J

Abstract

暂无摘要

MeSH Terms

Antigens/analysis Complement System Proteins/analysis Female Genes, Recessive Hemolysis Heterozygote Humans Hypoproteinemia/genetics Immunochemistry Immunodiffusion Infant, Newborn Male Maternal-Fetal Exchange Pedigree Pregnancy

Chemicals

Antigens Complement System Proteins

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Ruddy S

Klemperer M R

Rosen F S

Austen K F

Kumate J

References (14)

14 references, click to expand

Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum.
Immunochemistry. 1966 Mar;3(2):111-35 PMID: 5960883
Hereditary deficiency of the second component of complement in man: an immunochemical study.
J Immunol. 1969 Jan;102(1):168-71 PMID: 4179558
Hereditary deficiency of the second component of complement (C'2) in man.
J Clin Invest. 1966 Jun;45(6):880-90 PMID: 4161820
ISOLATION OF BETA IF-GLOBULIN FROM HUMAN SERUM AND ITS CHARACTERIZATION AS THE FIFTH COMPONENT OF COMPLEMENT.
J Exp Med. 1965 Aug 1;122:277-98 PMID: 14316946
Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies.
Anal Biochem. 1966 Apr;15(1):45-52 PMID: 5959431
Inherited c'2 deficiency in man: lack of immunochemically detectable c'2 protein in serums from deficient individuals.
Science. 1968 Sep 13;161(3846):1149-51 PMID: 17812292
Studies of an additional kindred with hereditary deficiency of the second component of human complement (C2) and description of a new method for the quantitation of C2.
J Immunol. 1968 Dec;101(6):1176-82 PMID: 5749189
THE MEASUREMENT OF SECOND COMPONENT OF HUMAN COMPLEMENT (C'2HU) BY ITS INTERACTION WITH EAC'1AGP,4GP CELLS.
J Immunol. 1964 Jun;92:946-57 PMID: 14210804
C3 inactivator of man. I. Hemolytic measurement by the inactivation of cell-bound C3.
J Immunol. 1969 Mar;102(3):533-43 PMID: 5813010
Complement-dependent biological functions in complement deficiency in man.
Lancet. 1966 Aug 13;2(7459):356-60 PMID: 4161719
CHROMATOGRAPHIC SEPARATION OF THE FIRST COMPONENT OF COMPLEMENT AND ITS ASSAY ON A MOLECULAR BASIS.
J Immunol. 1963 Dec;91:851-8 PMID: 14106311
Immune hemolysis: a simplified method for the preparation of EAC'4 with guinea pig or with human complement.
J Immunol. 1967 Aug;99(2):263-8 PMID: 4166243
The second component of human complement: its isolation, fragmentation by C'1 esterase, and incorporation into C'3 convertase.
J Exp Med. 1968 Sep 1;128(3):533-51 PMID: 5666963
Hereditary deficiency of the second component of complement (C'2) in man: further observations on a second kindred.
J Immunol. 1967 Jan;98(1):72-8 PMID: 6018771

Article Info

Journal

Immunology

Abbr.

Immunology

ISSN

0019-2805

Published

1970-06-00

Pages

943-54

Language

English

Region

England

NLM ID

0374672

PMCID

PMC1455728

Subset

External Links

PubMed source PMC Full Text View journal details

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Hereditary deficiency of the second component of complement (C2) in man: correlation of C2 haemolytic activity with immunochemical measurements of C2 protein.

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