Abstract
Systematic studies of the patterns of anatomic distribution, pathways of probable spread, and prognosis of the malignant lymphomas have been greatly aided by the development of new histopathologic classifications and the introduction of more sophisticated and precise diagnostic techniques, such as lymphangiography and laparotomy with splenectomy and retroperitoneal node biopsy. Concomitantly, megavoltage radiotherapy apparatus has made total-lymphoid radiotherapy feasible and practical, and the availability of a widening spectrum of chemotherapeutic agents has ushered in a new era of combination chemotherapy. Collectively, these diagnostic and therapeutic advances have already begun to yield a dramatic improvement in the prognosis of Hodgkin's disease and the other malignant lymphomas.
MeSH Terms
Adrenal Cortex Hormones/therapeutic use
Alkylating Agents/therapeutic use
Benzoates/therapeutic use
Biopsy
Hodgkin Disease/complications,diagnosis,drug therapy,pathology,radiotherapy
Humans
Lymph Nodes/diagnostic imaging
Lymphoma/classification,drug therapy,radiotherapy
Neoplasm Metastasis
Radiography
Radiotherapy, High-Energy
Splenectomy
Time Factors
Vinblastine/therapeutic use
Vincristine/therapeutic use
Chemicals
Adrenal Cortex Hormones
Alkylating Agents
Benzoates
Vincristine
Vinblastine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Rosenberg S A
Kaplan H S
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18 references, click to expand
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