On the mechanism of action of bleomycin. Strand scission of DNA caused by bleomycin and its binding to DNA in vitro.

Antibiotics, Antineoplastic/antagonists & inhibitors Carbon Isotopes Centrifugation, Density Gradient Chemical Phenomena Chemistry Chromatography Clone Cells Cobalt/pharmacology Copper/pharmacology DNA DNA, Bacterial Edetic Acid/pharmacology Escherichia coli Mercaptoethanol/pharmacology Peptides/antagonists & inhibitors Protein Binding RNA, Transfer Ribosomes/analysis Tritium Zinc/pharmacology

Antibiotics, Antineoplastic Carbon Isotopes DNA, Bacterial Peptides Tritium Cobalt Mercaptoethanol Copper DNA RNA, Transfer Edetic Acid Zinc