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PMID: 4994600 Published · ppublish English Journal Article

Induction of mutants of Staphylococcus aureus 100 with increased ability to produce enterotoxin A.

Journal of bacteriology ·Vol. 106 ·No. 1 ·1971-04-00 ·Pages 289-91

Friedman ME, Howard MB

Abstract

As a result of serial exposures to a mutagenic agent, N-methyl-N'-nitro-N-nitrosoguanidine, the yield of enterotoxin A produced by the last mutant in the series was increased nearly 20-fold over the amount produced by the parent Staphylococcus aureus 100.

MeSH Terms
Animals Colorimetry Culture Media Enterotoxins/adverse effects,biosynthesis Genetics, Microbial Guanidines Haplorhini Immune Sera Immunodiffusion Mutagens Mutation Nitroso Compounds Staphylococcus/drug effects,growth & development,immunology,isolation & purification,metabolism,radiation effects Ultraviolet Rays Vomiting/chemically induced
Chemicals
Culture Media Enterotoxins Guanidines Immune Sera Mutagens Nitroso Compounds
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Friedman M E
Howard M B
References (8)
8 references, click to expand
  1. Rapid, sensitive assay for staphylococcal enterotoxin and a comparison of serological methods.
    Appl Microbiol. 1968 Jul;16(7):1019-23 PMID: 4969665
  2. Production of high titers of enterotoxins for the routine testing of staphylococci.
    Appl Microbiol. 1970 Apr;19(4):698-9 PMID: 4986729
  3. PRODUCTION OF LARGE QUANTITIES OF ENTEROTOXIN B AND OTHER STAPHYLOCOCCAL TOXINS ON SOLID MEDIA.
    Acta Pathol Microbiol Scand. 1965;63:299-305 PMID: 14295449
  4. In vitro studies on staphylococcal enterotoxin production.
    J Bacteriol. 1960 Aug;80:265-70 PMID: 13835574
  5. CULTURE MEDIUM FOR THE PRODUCTION OF STAPHYLOCOCCAL ENTEROTOXIN A.
    J Bacteriol. 1963 Jul;86:18-23 PMID: 14051816
  6. SEROLOGICAL ASSAY OF CULTURE FILTRATES FOR STAPHYLOCOCCUS ENTEROTOXIN.
    J Bacteriol. 1963 Apr;85:955-6 PMID: 14044975
  7. Production of enterotoxin a.
    Appl Microbiol. 1966 Nov;14(6):966-72 PMID: 16349703
  8. Production of staphylococcal enterotoxins A, B, and C in various media.
    Appl Microbiol. 1969 Dec;18(6):1041-3 PMID: 5370657
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.106.1.289-291.1971
Published
1971-04-00
Pages
289-91
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC248676
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.106.1.289-291.1971 PMC Full Text View journal details
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