Urea cycle enzyme adaptation to dietary protein in primates.

Science (New York, N.Y.) ·Vol. 172 ·No. 3987 ·1971-06-04 ·Pages 1042-3

Nuzum CT, Snodgrass PJ

Abstract

Activities of the five hepatic enzymes of the urea cycle increased two- to threefold in monkeys on a 60 percent protein diet compared with levels in monkeys on an isocaloric 6 percent protein diet. Equal adaptation occurred in rats on the same diets. These enzyme activities in adult humans approximate those of monkeys on a similar protein intake.

MeSH Terms

Adaptation, Physiological Animals Arginase/metabolism Dietary Proteins Haplorhini/metabolism Ligases/metabolism Liver/enzymology Lyases/metabolism Ornithine Carbamoyltransferase/metabolism Physiology, Comparative Rats Succinates Urea/metabolism

Chemicals

Dietary Proteins Succinates Urea Ornithine Carbamoyltransferase Arginase Lyases Ligases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Nuzum C T

Snodgrass P J

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.172.3987.1042

Published

1971-06-04

Pages

1042-3

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.172.3987.1042 View journal details

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