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PMID: 50271 Published · ppublish ger English Abstract Journal Article

[Non-random position of homologous chromosomes (no. 9 and YY) in interphase nuclei of human fibroblasts (author's transl)].

Nichtzufällige Verteilung homologer Chromosomen (nr. 9 und YY) in Interphasekeren menschlicher Fibroblasten

Humangenetik ·Vol. 27 ·No. 2 ·1975-00-00 ·Pages 111-8

Spaeter M

Abstract

The position of chromosomes No. 9 and of the Y chromosomes in interphase nuclei was observed by means of the Giemsa-11 staining and the quinacrine mustard fluorescence staining respectively. 3 fibroblast cultures from normal female persons and 1 culture from a person with the karyotype 47/XYY were used. The distance between the two homologous chromosomes was compared with the theoretical expected distance between two points which are randomly positioned in a circular area. The distance between the chromosomes No. 9 as well as between the two Y chromosomes is significantly smaller than expected with a random position. This tendency for a somatic association is stronger in the case of the two Y chromosomes than in the two chromosomes No. 9.

MeSH Terms
Cell Nucleus Cells, Cultured Chromosomes, Human, 6-12 and X Female Fibroblasts/ultrastructure Fluorescence Humans Karyotyping Male Mathematics Mitosis Quinacrine Sex Chromosomes Staining and Labeling
Chemicals
Quinacrine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Spaeter M
References (28)
28 references, click to expand
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Article Info
Journal
Humangenetik
Abbr.
Humangenetik
ISSN
0018-7348
Published
1975-00-00
Pages
111-8
Language
ger
Region
Germany
NLM ID
7607154
Subset
IM
External Links
PubMed source
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