Crustacean color-change hormone: amino acid sequence and chemical synthesis.

Science (New York, N.Y.) ·Vol. 177 ·No. 4044 ·1972-07-14 ·Pages 173-5

Fernlund P, Josefsson L

Abstract

The blanching hormone of the prawn, Pandalus borealis, is pGlu-Leu-Asn-Phe-Ser-Pro-Gly-Trp-NH(2). Its structure was settled by a combination of mass spectrometry and Edman-dansyl analysis of a thermolysin fragment. Confirmation of the structure was obtained by chemical synthesis from amino acids. This neurosecreted hormone is active in picogram amounts when tested in shrimps.

MeSH Terms

Amino Acid Sequence Amino Acids/analysis Chromatography, Gel Chromatography, Thin Layer Decapoda Electrophoresis Hydrolysis Invertebrate Hormones/analysis,chemical synthesis Mass Spectrometry Peptides/analysis Spectrum Analysis Thermolysin Ultraviolet Rays

Chemicals

Amino Acids Invertebrate Hormones Peptides Thermolysin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Fernlund P

Josefsson L

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.177.4044.173

Published

1972-07-14

Pages

173-5

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.177.4044.173 View journal details

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Crustacean color-change hormone: amino acid sequence and chemical synthesis.

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