Cytological identification of the chromosomes involved in Searle's translocation and the location of the centromere in the X chromosome of the mouse.

Genetics ·Vol. 71 ·No. 4 ·1972-08-00 ·Pages 643-8

Eicher EM, Nesbitt MN, Francke U

Abstract

The autosome in Searle's X-autosome translocation has been shown to be chromosome 16. The breakpoint in chromosome 16 is slightly proximal to the middle and in the X is slightly distal to the middle.-Available evidence indicates that either Linkage Group XV or Linkage Group XIX is carried on chromosome 16.-The centromere of the X chromosome is at the spf end of the linkage group.

MeSH Terms

Animals Bone Marrow Cells Chromosome Aberrations Chromosome Mapping Colchicine Densitometry Genetic Linkage Karyotyping Mice Microscopy, Fluorescence Mustard Compounds Quinacrine Sex Chromosomes

Chemicals

Mustard Compounds Quinacrine Colchicine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Eicher E M

Nesbitt M N

Francke U

References (6)

6 references, click to expand

Cytological identification of the chromosome carrying the IXth linkage group (including H-2) in the house mouse.
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1594-7 PMID: 5283950
Arrangement of centromeres in mouse cells.
Chromosoma. 1971;34(1):73-87 PMID: 4105528
Assignment of four linkage groups to chromosomes in Mus musculus and a cytogenetic method for locating their centromeric ends.
Proc Natl Acad Sci U S A. 1971 Nov;68(11):2699-702 PMID: 5288246
Identification by quinacrine fluorescence of the chromosome carrying mouse linkage group I in the Cattanach translocation.
Genetics. 1971 Sep;69(1):129-32 PMID: 5133083
Banding patterns in mitotic chromosomes of tobacco mouse.
Exp Cell Res. 1972 Jan;70(1):263-8 PMID: 5008404
A MOUSE TRANSLOCATION SUPPRESSING SEX-LINKED VARIEGATION.
Cytogenetics. 1964;3:306-23 PMID: 14248461

Article Info

Journal

Genetics

Abbr.

Genetics

ISSN

0016-6731

DOI

10.1093/genetics/71.4.643

Published

1972-08-00

Pages

643-8

Language

English

Region

United States

NLM ID

0374636

PMCID

PMC1212800

Subset

External Links

PubMed source DOI: 10.1093/genetics/71.4.643 PMC Full Text View journal details

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Cytological identification of the chromosomes involved in Searle's translocation and the location of the centromere in the X chromosome of the mouse.

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