Viral and cellular surface antigens of murine leukemias and myelomas. Serological analysis by immunoelectron microscopy.
IMMUNOELECTRON MICROSCOPY (IEM) OF MOUSE CELLS WHICH WERE PRODUCTIVELY INFECTED WITH MURINE LEUKEMIA VIRUS (MULV) YIELDED THE FOLLOWING CONCLUSIONS: See PDF for Structure With two exceptions, the alloantigens H-2, theta, Ly-A, and Ly-B were not present on complete or incomplete virions produced by cells bearing these antigens.The exceptions were H-2(k) (but not H-2(b)) and theta both appeared on only a minority of virions and never on more than a small part of the circumference. The incidental discovery of an additional envelope antigen on virions produced by a BALB/c mouse myeloma but lacking from passage A Gross virions distinguishes these two viruses as MuLV subtypes; it also illustrates that IEM can be applied as a primary tool for antigenic analysis, as well as for its usual purpose of finding out where antigens are situated.
18 references, click to expand
-
The G (Gross) leukemia antigen.Cancer Res. 1965 Jul;25(6):813-9 PMID: 4284252
-
Antigens of tumors and leukemias induced by viruses.Fed Proc. 1965 Sep-Oct;24(5):1009-17 PMID: 5320101
-
Antigens of leukemias induced by naturally occurring murine leukemia virus: their relation to the antigens of gross virus and other murine leukemia viruses.J Exp Med. 1966 Oct 1;124(4):753-72 PMID: 4288480
-
Ly-A and Ly-B: two systems of lymphocyte isoantigens in the mouse.Proc R Soc Lond B Biol Sci. 1968 Jun 11;170(1019):175-93 PMID: 4385242
-
Use of hybrid antibody with anti-gamma-G and anti-ferritin specificities in locating cell surface antigens by electron microscopy.J Exp Med. 1968 Dec 1;128(6):1461-73 PMID: 4972125
-
Antigenic characterization of heterozygous mouse lymphomas after immunoselection in vivo.J Natl Cancer Inst. 1968 Dec;41(6):1411-29 PMID: 4882575
-
The cellular basis of immunological responses. A synthesis of some current views.Lancet. 1969 Aug 16;2(7616):367-71 PMID: 4183985
-
New visual markers of antibody for electron microscopy.Nature. 1969 Sep 13;223(5211):1158-9 PMID: 5810691
-
Antigenic structure of cell surfaces. An immunoferritin study of the occurrence and topography of H-2' theta, and TL alloantigens on mouse cells.J Exp Med. 1969 Nov 1;130(5):979-1001 PMID: 5347699
-
G (Gross) and H-2 cell-surface antigens: location on Gross leukemia cells by electron microscopy with visually labeled antibody.Proc Natl Acad Sci U S A. 1970 Mar;65(3):569-76 PMID: 5267138
-
Surface alloantigens of plasma cells.J Exp Med. 1970 Jun 1;131(6):1325-41 PMID: 5419273
-
Common properties of the oncogenic RNA viruses (oncornaviruses).Virology. 1970 Dec;42(4):1152-7 PMID: 5489229
-
Electron microscopic studies of tumor viruses. I. Entry of murine leukemia virus into mouse embryo fibroblasts.J Virol. 1971 Mar;7(3):395-406 PMID: 4101224
-
The G-IX system. A cell surface allo-antigen associated with murine leukemia virus; implications regarding chromosomal integration of the viral genome.J Exp Med. 1971 Jun 1;133(6):1334-55 PMID: 5576334
-
The entry of myxoviruses into the cell.Cold Spring Harb Symp Quant Biol. 1962;27:113-21 PMID: 13955208
-
Origin of lipids in influenza virus.Cold Spring Harb Symp Quant Biol. 1962;27:293-301 PMID: 13958354
-
THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES.J Exp Med. 1964 Sep 1;120:413-33 PMID: 14207060
-
GENETIC BASIS OF SUSCEPTIBILITY TO VIRAL LEUKAEMOGENESIS.Lancet. 1964 Dec 5;2(7371):1207-9 PMID: 14215561
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