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PMID: 50598 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

The neuraminidase yield-reduction bioassay of human other interferons.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) ·Vol. 149 ·No. 2 ·1975-06-00 ·Pages 433-8

Sedmak JJ, Grossberg SE, Jameson P

Abstract

The production of neuraminidase by the recombinant influenza virus X7(F1) in human monkey, rabbit, hamster, mouse, and chicken cell cultures is inhibited by interferon. Described is a new enzyme assay for neuraminidase that can be applied to the bioassay of interferons. The advantages of this interferon bioassay are its sensitivity, reproducibility, rapidity, and convenience.

MeSH Terms

Animals Biological Assay Cells, Cultured/enzymology Chickens Cricetinae Encephalomyocarditis virus Haplorhini Hemagglutination, Viral Humans Interferons Maus Elberfeld virus Mice Neuraminidase Orthomyxoviridae RNA Viruses Rabbits alpha-Fetoproteins

Chemicals

alpha-Fetoproteins Interferons Neuraminidase

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Sedmak J J

Grossberg S E

Jameson P

Article Info

Journal

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

Abbr.

Proc Soc Exp Biol Med

ISSN

0037-9727

DOI

10.3181/00379727-149-38822

Published

1975-06-00

Pages

433-8

Language

English

Region

United States

NLM ID

7505892

Subset

External Links

PubMed source DOI: 10.3181/00379727-149-38822 View journal details

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