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PMID: 506687 Published · ppublish English Case Reports Journal Article

Ultrastructure of neurofibrillary tangles in progressive supranuclear palsy.

Acta neuropathologica ·Vol. 48 ·No. 1 ·1979-10-00 ·Pages 27-30

Yagishita S, Itoh Y, Amano N, Nakano T, Saitoh A

Abstract

The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy. Straight tubules and twisted tubules were observed in both the cortical and subcortical neurofibrillary tangles. Most tubules appeared separately in each neuron but a few straight tubules were mixed with the twisted tubules in the cortical tangles. The implication and possible significance of this findings are discussed.

MeSH Terms
Aged Autopsy Brain Diseases/pathology Hippocampus/ultrastructure Humans Male Microscopy, Electron Neurofibrils/ultrastructure Pons/ultrastructure Substantia Nigra/ultrastructure
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Yagishita S
Itoh Y
Amano N
Nakano T
Saitoh A
References (10)
10 references, click to expand
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    Acta Neuropathol. 1977 Feb 28;37(2):177-81 PMID: 848281
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    J Neuropathol Exp Neurol. 1974 Jan;33(1):98-106 PMID: 4812327
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    Folia Psychiatr Neurol Jpn. 1974;28(3):187-96 PMID: 4611877
  9. Electron microscopic study of neurofibrillary tangles in Steele-Richardson-Olszewski syndrome.
    Acta Neuropathol. 1974;29(2):175-9 PMID: 4446944
  10. [Senile subcortical neurofibrillary degeneration with the presence of twisted tubules and straight filaments. Atypical form of progressive supranuclear paralysis].
    Rev Neurol (Paris). 1977 Jun-Jul;133(6-7):417-28 PMID: 929036
Article Info
Journal
Acta neuropathologica
Abbr.
Acta Neuropathol
ISSN
0001-6322
DOI
10.1007/BF00691787
Published
1979-10-00
Pages
27-30
Language
English
Region
Germany
NLM ID
0412041
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00691787 View journal details
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