Perturbation of the insulin receptor of isolated fat cells with proteolytic enzymes. Direct measurement of insulin-receptor interactions.

Adipose Tissue/cytology,drug effects,metabolism Animals Carbon Dioxide/biosynthesis Carbon Isotopes Chymotrypsin/antagonists & inhibitors,pharmacology Cold Temperature Enzyme Precursors/pharmacology Glucose/metabolism Insulin/metabolism,pharmacology Iodine Isotopes Isoflurophate/pharmacology Kinetics Papain/pharmacology Phospholipases/pharmacology Polysaccharides/pharmacology Protein Binding Rats Receptors, Drug Trypsin/pharmacology Trypsin Inhibitors/pharmacology

Carbon Isotopes Enzyme Precursors Insulin Iodine Isotopes Polysaccharides Receptors, Drug Trypsin Inhibitors Isoflurophate Carbon Dioxide Phospholipases Chymotrypsin Trypsin Papain Glucose