Colchicine, vinblastine and griseofulvin. Pharmacological studies with human leukocytes.

Acetates/metabolism Alkaloids/metabolism Blood Proteins/biosynthesis,metabolism Carbon Isotopes Carbon Radioisotopes Cell Fractionation Cell Nucleus/metabolism Cell-Free System Chromatography, Gel Chromatography, Thin Layer Colchicine/metabolism,pharmacology Cytoplasm/metabolism Depression, Chemical Drug Interactions Glutamates/metabolism,pharmacology Griseofulvin/metabolism,pharmacology Humans In Vitro Techniques Inclusion Bodies/metabolism Kinetics Leukocytes/cytology,drug effects,metabolism Lipids/biosynthesis Lysosomes/drug effects Microscopy, Electron Microtubules Nucleic Acids/biosynthesis Protein Binding RNA/biosynthesis Thymidine/metabolism Tritium Uridine/metabolism Valine/metabolism Vinblastine/metabolism,pharmacology Vincristine/pharmacology

Acetates Alkaloids Blood Proteins Carbon Isotopes Carbon Radioisotopes Glutamates Lipids Nucleic Acids Tritium Griseofulvin Vincristine Vinblastine RNA Valine Colchicine Thymidine Uridine