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PMID: 516740 Published · ppublish ger English Abstract Journal Article

[Preliminary findings with oral whooping cough vaccination in young infants (author's transl)].

Erste Ergebnisse mit oraler Keuchhustenimpfung bei jungen Säuglingen.

Wiener klinische Wochenschrift ·Vol. 91 ·No. 21 ·1979-11-09 ·Pages 717-20

Maurer H, Höfler KH, Hilbe W, Huber EG

Abstract

A preliminary report is presented on oral vaccination against whooping cough. 23 babies younger than, and 2 older than nine weeks and 12 newborn infants were vaccinated orally. No side effects were observed. Serum antibody titres did not increase markedly, but no child was seronegative after vaccination. An evident antibody titre rise to a higher level than in serum was found in the saliva. These results point toward an adequate local immunity. At present a definite statement about the efficacy of this oral vaccination is difficult to make. Further investigations are necessary.

MeSH Terms
Administration, Oral Antibodies, Bacterial/analysis Humans Infant Infant, Newborn Pertussis Vaccine/administration & dosage,therapeutic use Saliva/immunology Whooping Cough/immunology
Chemicals
Antibodies, Bacterial Pertussis Vaccine
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Maurer H
Höfler K H
Hilbe W
Huber E G
Article Info
Journal
Wiener klinische Wochenschrift
Abbr.
Wien Klin Wochenschr
ISSN
0043-5325
Published
1979-11-09
Pages
717-20
Language
ger
Region
Austria
NLM ID
21620870R
Subset
IM
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