Immunological reactivity of purified human parathyroid hormone.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 63 ·No. 3 ·1969-07-00 ·Pages 692-8

O'Riordan JL, Aurbach GD, Potts JT

Abstract

Immunological differences between human and bovine parathyroid hormones are detected with highly purified preparations of each hormone and several antisera produced against bovine parathyroid hormone. The immunological differences found show the necessity for using a reference preparation of human hormone in assays for parathyroid hormone in human serum.

MeSH Terms

Adenoma/immunology Animals Antigen-Antibody Reactions Cattle Humans Immunochemistry Iodine Isotopes Parathyroid Hormone/isolation & purification Parathyroid Neoplasms/immunology Protein Binding Radioimmunoassay Species Specificity

Chemicals

Iodine Isotopes Parathyroid Hormone

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

O'Riordan J L

Aurbach G D

Potts J T

References (5)

5 references, click to expand

Separation of antibody-bound and unbound peptide hormones labelled with iodine-131 by talcum powder and precipitated silica.
Nature. 1966 Oct 22;212(5060):355-7 PMID: 4291146
Isolation of parathyroid hormone after extraction with phenol.
J Biol Chem. 1959 Dec;234:3179-81 PMID: 13848891
IMMUNOASSAY OF BOVINE AND HUMAN PARATHYROID HORMONE.
Proc Natl Acad Sci U S A. 1963 May;49(5):613-7 PMID: 16591075
Immunochemical heterogeneity of parathyroid hormone in plasma.
J Clin Endocrinol Metab. 1968 Jul;28(7):1037-47 PMID: 5660255
Density gradient centrifugation of human and bovine parathyroid hormone.
Endocrinology. 1967 Sep;81(3):585-90 PMID: 4291805

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.63.3.692

Published

1969-07-00

Pages

692-8

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC223507

Subset

External Links

PubMed source DOI: 10.1073/pnas.63.3.692 PMC Full Text View journal details

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Immunological reactivity of purified human parathyroid hormone.

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