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PMID: 5269249 Published · ppublish English Journal Article

Regulation of repressor expression in lambda.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 66 ·No. 3 ·1970-07-00 ·Pages 855-62

Eisen H, Brachet P, Pereira da Silva L, Jacob F

Abstract

A new gene in bacteriophage lambda is described. The product of this gene cro prevents expression of immunity and regulates the expression of those genes to the left of the immunity region. cro(-) mutants have been isolated and characterized.

MeSH Terms
Coliphages/immunology Deoxyribonucleases/metabolism Genes, Regulator Lysogeny Mutation Operon
Chemicals
Deoxyribonucleases
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Eisen H
Brachet P
Pereira da Silva L
Jacob F
References (8)
8 references, click to expand
  1. Genetics and physiology of defective lysogeny in K12 (lambda): studies of early mutants.
    Virology. 1966 Oct;30(2):224-41 PMID: 5331503
  2. Integration-negative mutants of bacteriophage lambda.
    J Mol Biol. 1968 Feb 14;31(3):487-505 PMID: 5637199
  3. [On the early regulation of the lambda bacteriophage].
    C R Acad Sci Hebd Seances Acad Sci D. 1968 Mar 11;266(11):1176-8 PMID: 4968280
  4. The operators controlled by the lambda phage repressor.
    Proc Natl Acad Sci U S A. 1968 Aug;60(4):1282-7 PMID: 5244737
  5. Studies of the messenger RNA of bacteriophage lambda, I. Various species synthesized early after induction of the prophage.
    Proc Natl Acad Sci U S A. 1968 Nov;61(3):1013-20 PMID: 5246538
  6. [Genetic study of a mutation modifying the sensitivity of the lambda bacteriophage to immunity].
    Ann Inst Pasteur (Paris). 1968 Aug;115(2):145-58 PMID: 4880478
  7. Termination factor for RNA synthesis.
    Nature. 1969 Dec 20;224(5225):1168-74 PMID: 4902144
  8. NUCLEASE ACTIVITY IN DEFECTIVE LYSOGENS OF PHAGE MU. II. A HYPERACTIVE MUTANT.
    Proc Natl Acad Sci U S A. 1964 Oct;52:965-73 PMID: 14224401
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.66.3.855
Published
1970-07-00
Pages
855-62
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC283129
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.66.3.855 PMC Full Text View journal details
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