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PMID: 5286418 Published · ppublish ger Journal Article

[Autoradiographic and enzyme-chemical studies of the DNA synthesis in leukemia cells. II. Thymidine-kinase and 3H-thymidine labelling index under cytostatic therapy].

Autoradiographische und enzymchemische Untersuchungen der DNS-Synthese in Leukämiezellen. II. Thymidin-Kinase und 3H-Thymidin-Markierungsindex unter cytostatischer Therapie.

Klinische Wochenschrift ·Vol. 48 ·No. 13 ·1970-07-01 ·Pages 788-94

Wilmanns W, Hartje J

Abstract

暂无摘要

MeSH Terms
Adolescent Adult Autoradiography Cell Differentiation Cytarabine/therapeutic use DNA, Neoplasm/biosynthesis Female Histocytochemistry Humans Leukemia, Myeloid/drug therapy,enzymology Male Mercaptopurine/therapeutic use Methotrexate/therapeutic use Middle Aged Prednisolone/therapeutic use Thymidine/metabolism Thymidine Kinase/metabolism Tritium
Chemicals
DNA, Neoplasm Cytarabine Tritium Prednisolone Mercaptopurine Thymidine Kinase Thymidine Methotrexate
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Wilmanns W
Hartje J
References (22)
22 references, click to expand
  1. [Thymidine kinase in normal and leukemic myeloid cells].
    Klin Wochenschr. 1967 May 15;45(10):505-11 PMID: 5239336
  2. Proliferative activity of blast cells in leukemia and myelofibrosis. Morphological differences between proliferating and non-proliferating blast cells.
    Acta Med Scand. 1965 Sep;178(3):263-80 PMID: 5213256
  3. Study of the effect of therapy on cells in the blood of leukemic patients capable of incorporating H3-thymidine.
    J Lab Clin Med. 1962 Mar;59:412-8 PMID: 13870927
  4. [Effect and istribution of methotrexate in the human organism during leukemia treatment].
    Klin Wochenschr. 1968 Mar 15;46(6):281-96 PMID: 5245556
  5. THE MECHANISM OF ACTION OF THE FOLATE ANTAGONISTS IN MAN.
    Cancer Res. 1963 Sep;23:1286-306 PMID: 14070383
  6. Studies on thymidine kinase, thymidylate kinase, and deoxycytidylate deaminase of Chang liver cells.
    J Biol Chem. 1968 Apr 25;243(8):1979-84 PMID: 5646488
  7. Leukemic cell proliferation as determined by in vitro deoxyribonucleic acid synthesis.
    J Clin Invest. 1962 Feb;41:360-9 PMID: 13881943
  8. Uptake and phosphorylation of cytosine arabinoside by normal and leukemic human blood cells in vitro.
    Cancer Res. 1969 Feb;29(2):459-63 PMID: 5250069
  9. Drug effect in acute leukemia.
    J Clin Invest. 1969 Jun;48(6):1124-30 PMID: 5253748
  10. Thymidine phosphorylation and deoxyribonucleic acid synthesis in human leukaemic cells.
    Biochim Biophys Acta. 1962 Apr 2;55:547-9 PMID: 13868897
  11. Arabinofuranosylcytosine-induced stimulation of thymidine kinase and deoxycytidylic deaminase activities of mammalian cultures.
    Cancer Res. 1966 Sep;26(9):1859-66 PMID: 4958937
  12. Modes of uptake of methotrexate by normal and leukemic human leukocytes in vitro and their relation to drug response.
    Cancer Res. 1968 Mar;28(3):564-70 PMID: 5238559
  13. Variations in phosphokinase activities during the cell cycle in synchronous populations of HeLa cells.
    Nature. 1965 Jul 10;207(993):176-7 PMID: 5886110
  14. [Dihydrofolate reductase and thymidine kinase in the bone marrow under the influence of folic acid antagonists].
    Klin Wochenschr. 1967 Oct 1;45(19):987-94 PMID: 5245308
  15. Comparison of the proliferative capacity of acute leukaemia cells in bone marrow and blood.
    Nature. 1962 Mar 17;193:1085-6 PMID: 14471509
  16. Feedback inhibition of thymodine kinase by thymodine triphosphate.
    J Biol Chem. 1963 Apr;238:1467-74 PMID: 13964236
  17. Studies on the biosynthesis of deoxyribonucleic acid by extracts of mammalian cells. IV. The phosphorylation of thymidine.
    Biochim Biophys Acta. 1960 Dec 4;45:101-10 PMID: 13784139
  18. The effect of methotrexate on enzymes induced following partial hepatectomy.
    Cancer Res. 1969 Feb;29(2):366-72 PMID: 5765418
  19. [On the morphology and differentiation of leukemic cells].
    Klin Wochenschr. 1967 Feb 15;45(4):192-9 PMID: 4171923
  20. Coordinated changes in biochemical patterns: the effect of cytosine arabinoside and methotrexate on leukocytes from patients with acute granulocytic leukemia.
    Cancer Res. 1969 Mar;29(3):571-8 PMID: 5251290
  21. DNA synthesis and DNA content of leucocytes in acute leukaemia.
    Nature. 1967 Oct 14;216(5111):134-6 PMID: 6057219
  22. [Autoradiographic and enzyme-chemical studies of DNA synthesis in leukemia cells. I. Correlation of thymidine-kinase and 3 H-thymidine labelling index].
    Klin Wochenschr. 1970 Jul 1;48(13):780-8 PMID: 5286417
Article Info
Journal
Klinische Wochenschrift
Abbr.
Klin Wochenschr
ISSN
0023-2173
Published
1970-07-01
Pages
788-94
Language
ger
Region
Germany
NLM ID
2985205R
Subset
IM
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