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PMID: 5289000 Published · ppublish English Journal Article

Mutations altering chloroplast ribosome phenotype in Chlamydomonas. I. Non-mendelian mutations.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 67 ·No. 2 ·1970-10-00 ·Pages 1026-33

Gillham NW, Boynton JE, Burkholder B

Abstract

Uniparentally inherited mutations to antibiotic resistance and dependence in Chlamydomonas reinhardi exhibit an altered chloroplast ribosome phenotype. Genetic studies demonstrate an absolute correlation between the drug resistance or dependence and the ribosome phenotype in two such mutants.

MeSH Terms
Chlorophyta/analysis,drug effects Chloroplasts Drug Resistance, Microbial Mutation Phenotype RNA, Ribosomal/analysis Ribosomes/analysis Streptomycin/pharmacology
Chemicals
RNA, Ribosomal Streptomycin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Gillham N W
Boynton J E
Burkholder B
References (12)
12 references, click to expand
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    Bacteriol Rev. 1968 Dec;32(4 Pt 2):493-528 PMID: 4179192
  2. MITOTIC REPLICATION OF DEOXYRIBONUCLEIC ACID IN CHLAMYDOMONAS REINHARDI.
    Proc Natl Acad Sci U S A. 1960 Jan;46(1):83-91 PMID: 16590601
  3. Chloroplast structure and function in ac-20, a mutant strain of Chlamydomonas reinhardi. 3. Chloroplast ribosomes and membrane organization.
    J Cell Biol. 1970 Mar;44(3):547-62 PMID: 5415236
  4. MENDELIAN AND NON-MENDELIAN INHERITANCE OF STREPTOMYCIN RESISTANCE IN CHLAMYDOMONAS REINHARDI.
    Proc Natl Acad Sci U S A. 1954 May;40(5):356-63 PMID: 16589487
  5. Physical conservation of parental cytoplasmic DNA through meiosis in Chlamydomonas reinhardi.
    Proc Natl Acad Sci U S A. 1968 May;60(1):194-200 PMID: 5241520
  6. Assembly mapping of 30S ribosomal proteins from E. coli.
    Nature. 1970 Jun 27;226(5252):1214 PMID: 4912319
  7. Recombination of nonchromosomal mutations: a 3-point cross in the green alga Chlamydomonas reinhardi.
    Science. 1968 Nov 8;162(3854):683-4 PMID: 5693897
  8. Escherichia coli ribosomes: recent developments.
    Annu Rev Microbiol. 1969;23:387-426 PMID: 4900061
  9. Identification and functional characterization of the protein controlled by the streptomycin-resistant locus in E. coli.
    Nature. 1969 Apr 26;222(5191):333-9 PMID: 4181187
  10. Molecular weights of ribosomal RNA in relation to evolution.
    J Mol Biol. 1968 Dec;38(3):355-65 PMID: 5718556
  11. Induction of chromosomal and nonchromosomal mutations in Chlamydomonas reinhardi with N-methyl-N'-nitro-N-nitrosoguanidine.
    Genetics. 1965 Sep;52(3):529-37 PMID: 5863904
  12. Altered ribosomes in antibiotic-resistant mutants of E. coli.
    Cold Spring Harb Symp Quant Biol. 1969;34:95-100 PMID: 4245448
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.67.2.1026
Published
1970-10-00
Pages
1026-33
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC283308
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.67.2.1026 PMC Full Text View journal details
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