Ultraviolet-induced decrease in integration of Haemophilus influenzae transforming deoxyribonucleic acid in sensitive and resistant cells.
The decrease in integration of transforming deoxyribonucleic acid (DNA) caused by ultraviolet irradiation of the DNA was found to be independent of the presence or absence of excision repair in the recipient cell. Much of the ultraviolet-induced inhibition of integration resulted from the presence in the transforming DNA of pyrimidine dimers, as judged by the photoreactivability of the inhibition with yeast photoreactivating enzyme. The inhibition of integration made only a small contribution to the inactivation of transforming ability of the DNA by ultraviolet radiation.
16 references, click to expand
-
Repair of deoxyribonucleic acid in Haemophilus influenzae. I. X-ray sensitivity of ultraviolet-sensitive mutants and their behavior as hosts to ultraviolet-irradiated bacteriophage and transforming deoxyribonucleic acid.J Bacteriol. 1968 Feb;95(2):546-58 PMID: 5300300
-
Studies on transformations of Hemophilus influenzae. I. Competence.J Gen Physiol. 1961 Jul;44:1201-27 PMID: 13707010
-
Transformation and DNA size: two controlling parameters and the efficiency of the single strand intermediate.Cold Spring Harb Symp Quant Biol. 1968;33:643-5 PMID: 4389184
-
Killing of Haemophilus influenzae cells by integrated ultraviolet-induced lesions from transforming deoxyribonucleic acid.J Bacteriol. 1969 Dec;100(3):1284-8 PMID: 5308034
-
Pyrimidine dimers in ultraviolet-irradiated DNA's.J Mol Biol. 1966 May;17(1):237-54 PMID: 4289765
-
Fate of recipient deoxyribonucleic acid during transformation in Haemophilus influenzae.J Bacteriol. 1968 Nov;96(5):1718-24 PMID: 5303721
-
Dependence of Vegetative Recombination Among Haemophilus influenzae Bacteriophage on the Host Cell.J Virol. 1969 Sep;4(3):240-3 PMID: 16789099
-
The chemical nature of photoreactivable lesions in DNA.Proc Natl Acad Sci U S A. 1965 Jun;53(6):1430-6 PMID: 5324621
-
KINETICS OF THYMINE PHOTODIMERIZATION IN DNA.Biophys J. 1963 Sep;3:355-62 PMID: 14062455
-
Studies on the yeast photoreactivating enzyme. I. A method for the large scale purification and some properties of the enzyme.J Biol Chem. 1966 Jan 25;241(2):516-23 PMID: 5903745
-
Repair of DNA in Haemophilus influenzae. II. Excision, repair of single-strand breaks, defects in transformation, and host cell modification in UV-sensitive mutants.Cold Spring Harb Symp Quant Biol. 1968;33:209-18 PMID: 5305878
-
Genetic integration in the heterospecific transformation of Haemophilus influenzae cells by Haemophilus parainfluenzae deoxyribonucleic acid.J Bacteriol. 1968 Nov;96(5):1725-31 PMID: 4882021
-
On the nature of recombinants formed during transformation in Hemophilus influenzae.J Gen Physiol. 1966 Jul;49(6):197-209 PMID: 5298073
-
Development of competence of Haemophilus influenzae.J Bacteriol. 1965 Oct;90(4):911-20 PMID: 5294817
-
Decrease in integration of transforming DNA of Hemophilus influenzae following ultraviolet irradiation.J Mol Biol. 1965 Sep;13(2):611-3 PMID: 5295583
-
Evidence that ultraviolet-induced thymine dimers in DNA cause biological damage.Proc Natl Acad Sci U S A. 1962 Jul 15;48:1250-7 PMID: 13910967
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: [email protected]
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
