Identification of the vasopressin producing and of the oxytocin producing neurons in the hypothalamic magnocellular neurosecretroy system of the rat.

Cell and tissue research ·Vol. 164 ·No. 2 ·1975-12-02 ·Pages 153-62

Vandesande F, Dierickx K

Abstract

Immuno-enzyme histochemical investigations showed that, in the magnocellular hypothalamo-hypophysial neurosecretory system of the rat, vasopressin and oxytocin are synthetized in separate neurons. Both the vasopressin neurons and the oxytocin neurons are present in both the supraoptic and the paraventricular nuclei in about the same number. Preferential location of the two kinds of rat neurosecretory neurons is not as obvious as in the bovine hypothalamus. Their perikarya do not show distinct morphological differences. The two kinds of neurosecretory perikarya are the origin of separate vasopressin-containing and oxytocin-containing axons respectively. In the neural lobe, the distribution of the two different types of axons is described.

MeSH Terms

Animals Female Fluorescent Antibody Technique Histocytochemistry Hypothalamo-Hypophyseal System/cytology Male Neurons/metabolism Oxytocin/biosynthesis Paraventricular Hypothalamic Nucleus/cytology Rats/anatomy & histology Staining and Labeling Supraoptic Nucleus/cytology Vasopressins/biosynthesis

Chemicals

Vasopressins Oxytocin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Vandesande F

Dierickx K

References (8)

8 references, click to expand

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Identification of the vasopressin-neurophysin II and the oxytocin-neurophysin I producing neurons in the bovine hypothalamus.
Cell Tissue Res. 1975;156(2):189-200 PMID: 1122515
The development of a radioimmunoassay for oxytocin: radioiodination, antibody production and separation techniques.
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Ultrastructural immunocytochemistry with unlabeled antibodies and the peroxidase-antiperoxidase complex. A technique more sensitive than radioimmunoassay.
J Histochem Cytochem. 1973 Sep;21(9):825-33 PMID: 4126285
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J Histochem Cytochem. 1973 Oct;21(10):855-94 PMID: 4356692
The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes.
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Article Info

Journal

Cell and tissue research

Abbr.

Cell Tissue Res

ISSN

0302-766X

DOI

10.1007/BF00218970

Published

1975-12-02

Pages

153-62

Language

English

Region

Germany

NLM ID

0417625

Subset

External Links

PubMed source DOI: 10.1007/BF00218970 View journal details

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Identification of the vasopressin producing and of the oxytocin producing neurons in the hypothalamic magnocellular neurosecretroy system of the rat.

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