Allograft survival: effect of antiserums to thymus glands and lymphocytes.

Science (New York, N.Y.) ·Vol. 150 ·No. 3700 ·1965-11-26 ·Pages 1181-2

Nagaya H, Sieker HO

Abstract

Although antiserums to lymphocytes and thymus cells have similar effects on lymphocytes and thymocytes in vitro, the antiserum to thymus has more persistent lymphopenic effect in vivo and prolongs allograft survival time more markedly. Since only thymus glands of animals treated with antiserum to thymus showed depletion of small lymphocytes, antibody to thymic humoral factor may be operational.

MeSH Terms

Animals Immune Sera/pharmacology In Vitro Techniques Lymphocytes Rabbits Rats Skin Transplantation Thymus Gland/cytology Transplantation Immunology Transplantation, Homologous

Chemicals

Immune Sera

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Nagaya H

Sieker H O

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.150.3700.1181

Published

1965-11-26

Pages

1181-2

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.150.3700.1181 View journal details

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Allograft survival: effect of antiserums to thymus glands and lymphocytes.

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