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PMID: 532495 Published · ppublish ger English Abstract Journal Article

[Effect of cesium ions on the electrotropic actions of acetylcholine in the rabbit atrium].

Elektrotrope Azetylcholinwirkungen auf das Vorhofmyokard unter dem Einfluss von Caesium-Ionen.

Acta biologica et medica Germanica ·Vol. 38 ·No. 8 ·1979-00-00 ·Pages 1175-82

Nilius B, Boldt W

Abstract

Cs+ (15-20 mM) decreases the electrotropic vagal effects on an isolated vagal innervated rabbit atrium. By means of investigating the action potentials and the phase plane trajectories of trabeculae from the rabbit atrium using a modified single sucrose gap technique the anomalous rectification disappears and also the effect of acetylcholine (ACh) on action potential duration. We presume that the anomalous rectification should be a necessary condition of electrotropic vagal (ACh) action on the rabbit atrium.

MeSH Terms
Acetylcholine/pharmacology Action Potentials/drug effects Animals Atrial Function Cesium/pharmacology Heart Atria/drug effects Kinetics Mathematics Myocardial Contraction/drug effects Rabbits
Chemicals
Cesium Acetylcholine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Nilius B
Boldt W
Article Info
Journal
Acta biologica et medica Germanica
Abbr.
Acta Biol Med Ger
ISSN
0001-5318
Published
1979-00-00
Pages
1175-82
Language
ger
Region
Germany
NLM ID
0370276
Subset
IM
External Links
PubMed source
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