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PMID: 5360583 Published · ppublish English Journal Article

Cytosine to thymine transitions from decay of cytosine-5-3H in bacteriophage S13.

Science (New York, N.Y.) ·Vol. 166 ·No. 3913 ·1969-12-26 ·Pages 1629-31

Funk F, Person S

Abstract

Decay of cytosine-5-(3)H incorporated into bacteriophage S13 DNA causes a molectular rearrangement of the cytosine molecutle undergoing the decay. The molecular rearrangement produces a cytosine to thyimine coding change with at efficiency approaching one. Decay of either thymidine-(methyl)-(3)H or cytosine-6-(3)H is less than 1 percent as effective in calusing either cytosine to thymine or thymine to cytosine transitions.

MeSH Terms
Centrifugation, Density Gradient Coliphages/metabolism Cytosine/metabolism Genetic Code Mutation Thymine/metabolism Tritium
Chemicals
Tritium Cytosine Thymine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Funk F
Person S
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1969-12-26
Pages
1629-31
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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