Some properties of the beta-lactamase genes in Staphylococcus epidermidis.

Applied microbiology ·Vol. 18 ·No. 4 ·1969-10-00 ·Pages 628-30

Baldwin JN, Strickland RH, Cox MF

Abstract

Eighty-three per cent of 200 different freshly isolated cultures of Staphylococcus epidermidis produced beta lactamase. Growth in the presence of acridine orange or ethidium bromide or growth at 44 C resulted in a high frequency of loss of the beta lactamase genes in some strains of S. epidermidis. The relationship between beta-lactamase production and resistance to mercuric, cadmium and arsenate ions differed from that observed in Staphylococcus aureus. It is postulated that the genes for beta lactamase in certain strains of S. epidermidis are on a plasmid.

MeSH Terms

Acridines/pharmacology Adult Arsenic/pharmacology Cadmium/pharmacology Drug Resistance, Microbial Genes Genetics, Microbial Humans Mercury/pharmacology Mutation Phenanthridines/pharmacology Staphylococcus/drug effects,enzymology,isolation & purification

Chemicals

Acridines Phenanthridines Cadmium Mercury Arsenic

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Baldwin J N

Strickland R H

Cox M F

References (11)

11 references, click to expand

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Article Info

Journal

Applied microbiology

Abbr.

Appl Microbiol

ISSN

0003-6919

DOI

10.1128/am.18.4.628-630.1969

Published

1969-10-00

Pages

628-30

Language

English

Region

United States

NLM ID

7605802

PMCID

PMC378049

Subset

External Links

PubMed source DOI: 10.1128/am.18.4.628-630.1969 PMC Full Text

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Some properties of the beta-lactamase genes in Staphylococcus epidermidis.

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