In vitro studies of cell-mediated immunity. I. Induction of lymphocyte transformation by a soluble "mitogenic" factor derived from interaction of sensitized guinea-pig lymphoid cells with specific antigen.

Immunology ·Vol. 18 ·No. 4 ·1970-04-00 ·Pages 599-610

Wolstencroft RA, Dumonde DC

Abstract

暂无摘要

MeSH Terms

Animals Antibody Formation Antigen-Antibody Reactions Antigens Culture Techniques Freund's Adjuvant Guinea Pigs Immunity Immunization Lymph Nodes/cytology Lymphocyte Activation Lymphocytes/immunology,metabolism Mitosis Thymidine/metabolism Tritium

Chemicals

Antigens Tritium Freund's Adjuvant Thymidine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Wolstencroft R A

Dumonde D C

References (15)

15 references, click to expand

Mechanism of a reaction in vitro associated with delayed-type hypersensitivity.
Science. 1966 Jul 1;153(3731):80-2 PMID: 5938421
A factor stimulating DNA synthesis derived from the medium of leukocyte cultures.
Nature. 1965 Nov 20;208(5012):794-5 PMID: 5868897
Delayed hypersensitivity in the guinea-pig to a protein-hapten conjugate and its relationship to in vitro transformation of lymph node, spleen, thymus and peripheral blood lymphocytes.
Immunology. 1967 Jan;12(1):89-102 PMID: 6017286
Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction.
Proc Natl Acad Sci U S A. 1966 Jul;56(1):72-7 PMID: 5229858
The role of the macrophage in delayed hypersensitivity.
Br Med Bull. 1967 Jan;23(1):9-14 PMID: 5342388
Sequential changes in the relative affinity of antibodies synthesized during the immune response.
J Exp Med. 1967 Dec 1;126(6):1161-83 PMID: 4168368
Reactions in vivo and in vitro produced by a soluble substance associated with delayed-type hypersensitivity.
Proc Natl Acad Sci U S A. 1968 Mar;59(3):756-62 PMID: 5238658
Lymphocyte cytotoxicity in vitro: activation and release of a cytotoxic factor.
Nature. 1968 Jun 29;218(5148):1253-4 PMID: 5656652
Cell migration inhibition factor released by antigen from human peripheral lymphocytes.
Nature. 1968 Aug 17;219(5155):755-7 PMID: 5667078
Lymphocyte in vitro cytotoxicity: characterization of human lymphotoxin.
Proc Natl Acad Sci U S A. 1968 Dec;61(4):1250-5 PMID: 5249808
Demonstration of specific induction of erythrocytes phagocytosis by macrophates from normal, non-sensitized rabbits by a factor released from lymph node cells of immunized rabbits.
Experientia. 1968 Sep 15;24(9):948-9 PMID: 5709049
Leukotactic factor produced by sensitized lymphocytes.
Science. 1969 Mar 7;163(3871):1079-81 PMID: 5764874
Induction of DNA synthesis in normal human lymphocyte cultures by antigen-antibody complexes.
Clin Exp Immunol. 1969 Jan;4(1):65-82 PMID: 4182356
"Lymphokines": non-antibody mediators of cellular immunity generated by lymphocyte activation.
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Lymphocyte mitogenic factor in man.
Nature. 1969 Oct 4;224(5214):43-4 PMID: 5822904

Article Info

Journal

Immunology

Abbr.

Immunology

ISSN

0019-2805

Published

1970-04-00

Pages

599-610

Language

English

Region

England

NLM ID

0374672

PMCID

PMC1455489

Subset

External Links

PubMed source PMC Full Text View journal details

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In vitro studies of cell-mediated immunity. I. Induction of lymphocyte transformation by a soluble "mitogenic" factor derived from interaction of sensitized guinea-pig lymphoid cells with specific antigen.

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