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PMID: 5428782 Published · ppublish English Journal Article

Vancomycin for staphylococcal shunt site infections in patients on regular haemodialysis.

British medical journal ·Vol. 3 ·No. 5714 ·1970-07-11 ·Pages 80-2

Eykyn S, Phillips I, Evans J

Abstract

Six anuric patients with Scribner shunt site infections were treated by intermittent infusion of vancomycin into the shunt, and a satisfactory clinical response was obtained in five. Serum levels of the antibiotic were estimated frequently. From estimating serum levels and the minimum inhibitory concentrations of vancomycin for a range of hospital staphylococci a dose of 1g. vancomycin every seven days is recommended as a suitable schedule for treating staphylococcal infection in this situation.

MeSH Terms
Adult Arteriovenous Shunt, Surgical/adverse effects Female Humans Male Microbial Sensitivity Tests Renal Dialysis/adverse effects Staphylococcal Infections/drug therapy Vancomycin/administration & dosage,blood,therapeutic use
Chemicals
Vancomycin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Eykyn S
Phillips I
Evans J
References (4)
4 references, click to expand
  1. Persistence of vancomycin in the blood during renal failure and its treatment by hemodialysis.
    N Engl J Med. 1966 May 12;274(19):1047-51 PMID: 5929886
  2. Vancomycin, a new antibiotic. I. Chemical and biologic properties.
    Antibiot Annu. 1955-1956;3:606-11 PMID: 13355336
  3. Antibiotic therapy of bacterial endocarditis. VII. Vancomycin for acute micrococcal endocarditis; preliminary report.
    Proc Staff Meet Mayo Clin. 1958 Apr 2;33(7):172-81 PMID: 13542649
  4. Vancomycin: report on treatment of patients with severe staphylococcal infections.
    Br Med J. 1959 May 2;1(5130):1144-9 PMID: 13638652
Article Info
Journal
British medical journal
Abbr.
Br Med J
ISSN
0007-1447
Published
1970-07-11
Pages
80-2
Language
English
Region
England
NLM ID
0372673
PMCID
PMC1701050
Subset
IM
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