Cephaloridine serum levels in patients on maintenance haemodialysis.

British medical journal ·Vol. 2 ·No. 5702 ·1970-04-18 ·Pages 149-51

Curtis JR, Marshall MJ

Abstract

Cephaloridine serum half-life was determined in 11 patients undergoing maintenance haemodialysis. Three of them were anephric. The mean cephaloridine half-life was 10.4 hours. There was an inverse correlation between cephaloridine half-life and the duration of maintenance haemodialysis treatment. Reasons for this are discussed.The effect of haemodialysis with the Kiil dialyser on cephaloridine half-life was studied in three patients.Dosage recommendations for patients on maintenance haemodialysis are suggested.

MeSH Terms

Adolescent Adult Cephaloridine/administration & dosage,blood,metabolism Creatinine/metabolism Female Humans Kidney Failure, Chronic/therapy Male Metabolic Clearance Rate Nephrectomy Renal Dialysis Time Factors Warfarin/therapeutic use

Chemicals

Warfarin Creatinine Cephaloridine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Curtis J R

Marshall M J

References (2)

2 references, click to expand

Excretion of cephaloridine and cephalothin in patients with renal impairment.
N Engl J Med. 1966 Mar 24;274(12):654-6 PMID: 17926378
Cephaloridine therapy as related to renal function.
Antimicrob Agents Chemother (Bethesda). 1965;5:922-32 PMID: 5883518

Article Info

Journal

British medical journal

Abbr.

Br Med J

ISSN

0007-1447

DOI

10.1136/bmj.2.5702.149

Published

1970-04-18

Pages

149-51

Language

English

Region

England

NLM ID

0372673

PMCID

PMC1699988

Subset

External Links

PubMed source DOI: 10.1136/bmj.2.5702.149 PMC Full Text

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Cephaloridine serum levels in patients on maintenance haemodialysis.

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