Perfusion treatment for malignant melanoma of the extremity.

Amputation Bone Marrow Diseases/etiology Chemotherapy, Cancer, Regional Perfusion/adverse effects,instrumentation Extracorporeal Circulation Extremities Fascia Female Hepatitis B/etiology Humans Lymph Node Excision Lymphatic Metastasis Male Melanoma/mortality,therapy Melphalan/therapeutic use Methods Necrosis/etiology Neoplasm Recurrence, Local Neuritis/etiology Prognosis Thrombophlebitis/etiology

Melphalan