Rapid method for the determination of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in small regions of rat brain.

British journal of pharmacology ·Vol. 39 ·No. 3 ·1970-07-00 ·Pages 653-5

Curzon G, Green AR

Abstract

A rapid and sensitive method for measuring 5-hydroxytryptamine and 5-hydroxyindoleacetic acid, using o-phthalaldehyde and L-cysteine, is presented, enabling both compounds to be measured in small areas of rat brain.

MeSH Terms

Aldehydes Animals Brain Chemistry Cysteine Fluorometry Hydroxyindoleacetic Acid/analysis Male Methods Rats Serotonin/analysis

Chemicals

Aldehydes Serotonin Hydroxyindoleacetic Acid Cysteine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Curzon G

Green A R

References (13)

13 references, click to expand

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Int J Neuropharmacol. 1968 May;7(3):275-81 PMID: 5720517
Simultaneous estimation of 5-hydroxytryptamine and 5-hydroxyindol-3-acetic acid in rat brain.
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Solvent extraction method for simultaneous determination of norepinephrine, dopamine, serotonin, and 5-hydroxyindoleacetic acid in a single mouse brain.
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A spectrofluorometric method for the simultaneous determination of 2-(5-hydroxyindol-3-yl) ethylamine (serotonin) and 5-hydroxyindol-3-yl-acetic acid in the brain.
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A method for the simultaneous determination of 5-hydroxy-3-indole-acetic acid (5-HIAA) and 5-hydroxytryptamine (5-HT) in brain tissue and cerebrospinal fluid.
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Article Info

Journal

British journal of pharmacology

Abbr.

Br J Pharmacol

ISSN

0007-1188

DOI

10.1111/j.1476-5381.1970.tb10373.x

Published

1970-07-00

Pages

653-5

Language

English

Region

England

NLM ID

7502536

PMCID

PMC1702616

Subset

External Links

PubMed source DOI: 10.1111/j.1476-5381.1970.tb10373.x PMC Full Text View journal details

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Rapid method for the determination of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in small regions of rat brain.

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