The effect of cycloheximide upon polyribosome stability in two yeast mutants defective respectively in the initiation of polypeptide chains and in messenger RNA synthesis.

Molecular & general genetics : MGG ·Vol. 106 ·No. 4 ·1970-00-00 ·Pages 347-61

Hartwell LH, Hutchison HT, Holland TM, McLaughlin CS

Abstract

暂无摘要

MeSH Terms

Amino Acids/metabolism Carbon Isotopes Centrifugation, Density Gradient Cycloheximide/pharmacology Kinetics Mutation Peptide Biosynthesis RNA/biosynthesis RNA, Messenger/biosynthesis Ribosomes/drug effects Saccharomyces Temperature

Chemicals

Amino Acids Carbon Isotopes RNA, Messenger RNA Cycloheximide

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Hartwell L H

Hutchison H T

Holland T M

McLaughlin C S

References (20)

20 references, click to expand

Effects of cycloheximide on ribosomal RNA synthesis in yeast.
Biochem Biophys Res Commun. 1969 Feb 21;34(4):488-94 PMID: 5776394
Ribonucleic acid synthesis in yeast. The effect of cycloheximide on the synthesis of ribonucleic acid in Saccharomyces carlsbergensis.
Biochem J. 1966 Jun;99(3):566-81 PMID: 5964958
Macromolecule synthesis in yeast spheroplasts.
J Bacteriol. 1967 Nov;94(5):1697-705 PMID: 6066050
Macromolecule synthesis in temperature-sensitive mutants of yeast.
J Bacteriol. 1967 May;93(5):1662-70 PMID: 5337848
Breakdown of rat-liver ergosomes in vivo after actinomycin inhibition of messenger RNA synthesis.
Science. 1963 Apr 12;140(3563):180-3 PMID: 13978666
Effects of cycloheximide and 5-fluorouracil on the synthesis of ribonucleic acid in yeast.
Biochim Biophys Acta. 1968 Dec 17;169(2):297-305 PMID: 5702962
Temperature-sensitive mutants of yeast exhibiting a rapid inhibition of protein synthesis.
J Bacteriol. 1968 Nov;96(5):1664-71 PMID: 5726307
The mechanism of sodium fluoride and cycloheximide inhibition of hemoglobin biosynthesis in the cell-free reticulocyte system.
J Mol Biol. 1966 Oct 28;21(1):51-69 PMID: 5969765
A study of the relationship between polyribosomes and messenger RNA in Escherichia coli.
J Mol Biol. 1968 Mar 14;32(2):183-200 PMID: 4868419
Modified ribosomes conferring resistance to cycloheximide in mutants of Saccharomyces cerevisiae.
J Mol Biol. 1967 Jun 14;26(2):347-50 PMID: 6034778
A mutant of yeast apparently defective in the initiation of protein synthesis.
Proc Natl Acad Sci U S A. 1969 Feb;62(2):468-74 PMID: 5256225
Messenger RNA and RNA transcription time.
J Mol Biol. 1967 Dec 14;30(2):349-70 PMID: 4172200
Effects of cycloheximide on polyribosome function in reticulocytes.
J Mol Biol. 1967 Jul 14;27(1):57-72 PMID: 6033612
Temperature-sensitive yeast mutant defective in ribonucleic acid production.
J Bacteriol. 1969 Sep;99(3):807-14 PMID: 5370278
A multiple ribosomal structure in protein synthesis.
Proc Natl Acad Sci U S A. 1963 Jan 15;49:122-9 PMID: 13998950
The effect of actidione and other antifungal agents on nucleic acid and protein synthesis in Saccharomyces carlsbergensis.
J Gen Microbiol. 1958 Dec;19(3):497-506 PMID: 13611192
SITE OF ACTION OF CYCLOHEXIMIDE IN CELLS OF SACCHAROMYCES PASTORIANUS. II. THE NATURE OF INHIBITION OF PROTEIN SYNTHESIS IN A CELL-FREE SYSTEM.
Biochim Biophys Acta. 1964 May 18;87:83-9 PMID: 14171041
Ribosome formation in HeLa cells in the absence of protein synthesis.
J Mol Biol. 1966 Aug;19(2):373-82 PMID: 5969072
Isopycnic separation of subcellular components from poliovirus-infected and normal HeLa cells.
Science. 1968 Nov 1;162(3853):572-4 PMID: 4303295
Accumulation of RNA with a DNA like base composition in Saccharomyces carlsbergensis in the presence of cycloheximide.
Biochem Biophys Res Commun. 1965 May 18;19(5):582-6 PMID: 5834709

Article Info

Journal

Molecular & general genetics : MGG

Abbr.

Mol Gen Genet

ISSN

0026-8925

DOI

10.1007/BF00324052

Published

1970-00-00

Pages

347-61

Language

English

Region

Germany

NLM ID

0125036

Subset

External Links

PubMed source DOI: 10.1007/BF00324052

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The effect of cycloheximide upon polyribosome stability in two yeast mutants defective respectively in the initiation of polypeptide chains and in messenger RNA synthesis.

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