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PMID: 5549097 Published · ppublish English Journal Article

Mechanisms of anion and cation permeations in the resting membrane of a barnacle muscle fiber.

The Journal of general physiology ·Vol. 57 ·No. 4 ·1971-04-00 ·Pages 408-34

Hagiwara S, Toyama K, Hayashi H

Abstract

The resting membrane of a barnacle muscle fiber is mostly permeable to cations in a solution of pH 7.7 whereas it becomes primarily permeable to anions if the pH is below 4.0. Mechanisms of ion permeation for various monovalent cations and anions were investigated at pH 7.7 and 3.9, respectively. Permeability ratios were obtained from the relationship between the membrane potential and the concentration of the test ions, and ionic conductances from current-voltage relations of the membrane. The permeability sequence for anions (SCN > I > NO(3) > Br > ClO(3) > Cl > BrO(3) > IO(3)) was different from the conductance sequence for anions (Br, Cl > ClO(3), NO(3) > SCN). In contrast, the permeability and conductance sequences were identical for cations (K > Rb > Cs > Na > Li). The results suggest that anion permeation is governed by membrane charges while cation permeation is via some electrically neutral mechanism.

MeSH Terms
Animals Cell Membrane Permeability Crustacea Electric Conductivity Electrophysiology Hydrogen-Ion Concentration Ions/metabolism Membrane Potentials Myofibrils/metabolism,physiology
Chemicals
Ions
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hagiwara S
Toyama K
Hayashi H
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22 references, click to expand
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Article Info
Journal
The Journal of general physiology
Abbr.
J Gen Physiol
ISSN
0022-1295
DOI
10.1085/jgp.57.4.408
Published
1971-04-00
Pages
408-34
Language
English
Region
United States
NLM ID
2985110R
PMCID
PMC2203109
Subset
IM
External Links
PubMed source DOI: 10.1085/jgp.57.4.408 PMC Full Text View journal details
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