Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and "agitation" in rats.

Acepromazine/pharmacology Amphetamine/antagonists & inhibitors Animals Apomorphine/antagonists & inhibitors Behavior, Animal/drug effects Benperidol/pharmacology Chlorpromazine/pharmacology Chlorprothixene/pharmacology Fluphenazine/pharmacology Haloperidol/pharmacology Male Mastication/drug effects Methods Motor Activity/drug effects Norepinephrine/antagonists & inhibitors Perphenazine/pharmacology Phenothiazines/pharmacology Prochlorperazine/pharmacology Promazine/pharmacology Rats Thiazines/pharmacology Thioridazine/pharmacology Tranquilizing Agents/administration & dosage,pharmacology Trifluoperazine/pharmacology Triflupromazine/pharmacology Trimeprazine/pharmacology

Phenothiazines Thiazines Tranquilizing Agents Trifluoperazine Acepromazine Trimeprazine Benperidol Chlorprothixene Amphetamine Perphenazine Haloperidol Apomorphine Thioridazine Promazine Triflupromazine Fluphenazine Chlorpromazine Norepinephrine Prochlorperazine