An association between actin and the major histocompatibility antigen H-2.

Nature ·Vol. 273 ·No. 5660 ·1978-05-25 ·Pages 274-8

Koch GL, Smith MJ

Abstract

P815 cells spontaneously shed material (exfoliate) in which actin is the major protein. The exfoliate also contains H-2. The association between actin and H-2 is stable even in the presence of detergent, indicating that protein-protein interactions exist between the actin and H-2. The exfoliate probably consists of highly purified microvilli.

MeSH Terms

Actins/metabolism Cell Line Cytoskeleton/metabolism Exocytosis H-2 Antigens Membrane Proteins/metabolism Microvilli/metabolism

Chemicals

Actins H-2 Antigens Membrane Proteins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Koch G L

Smith M J

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/273274a0

Published

1978-05-25

Pages

274-8

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/273274a0 View journal details

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An association between actin and the major histocompatibility antigen H-2.

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