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PMID: 5677536 Published · ppublish English Journal Article

Hypothalamic motivational systems: fixed or plastic neural circuits?

Science (New York, N.Y.) ·Vol. 162 ·No. 3851 ·1968-10-18 ·Pages 377-9

Wise RA

Abstract

Eating and drinking were elicited by electrical stimulation through the same electrode in the hypothalamus of a satiated rat. Intensity thresholds for eliciting eating and drinking were different, and both thresholds decreased with repeated testing. These findings suggest an alternative to the hypothesis that the neural organization of hypothalamic drive systems is modified by experience.

MeSH Terms
Animals Drinking Drive Eating Electric Stimulation Hypothalamus/anatomy & histology,physiology Learning Neurons/anatomy & histology,physiology Nutritional Physiological Phenomena Psychophysiology Rats Thirst
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Wise R A
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1968-10-18
Pages
377-9
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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