Frame shift mutations near the beginning of the lysozyme gene of bacteriophage T4.

Science (New York, N.Y.) ·Vol. 162 ·No. 3855 ·1968-11-15 ·Pages 807-8

Okada Y, Streisinger G, Emrich J, Newton J, Tsugita A, Inouye M

Abstract

A pair of frame shift mutations in the lysozyme gene of bacteriophage T4 results in the substitution of a glutamyl-tyrosyl sequence for the asparagine residue that is the penultimate amino-terminal amino acid in the lysozyme of the wild-type strain. One of the mutations has been identified as the insertion of two bases, the other as the insertion of a single base.

MeSH Terms

Amino Acid Sequence Asparagine Chromatography, Ion Exchange Chromatography, Paper Coliphages Genes Genetic Code Genetics, Microbial Glutamates Muramidase/analysis Mutation Peptides/analysis Trypsin Tyrosine

Chemicals

Glutamates Peptides Tyrosine Asparagine Muramidase Trypsin

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Okada Y

Streisinger G

Emrich J

Newton J

Tsugita A

Inouye M

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.162.3855.807

Published

1968-11-15

Pages

807-8

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.162.3855.807 View journal details

Analysis Services

Frame shift mutations near the beginning of the lysozyme gene of bacteriophage T4.

Contact

WeChat Official Account