Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?

Cells, Cultured Chromosome Aberrations Chromosome Deletion Drug Resistance/radiation effects Female Genes Glucosephosphate Dehydrogenase/genetics Hypoxanthine Phosphoribosyltransferase/deficiency,genetics Mutation/radiation effects Sex Chromosomes/radiation effects Thioguanine/pharmacology X Chromosome/radiation effects,ultrastructure

Glucosephosphate Dehydrogenase Hypoxanthine Phosphoribosyltransferase Thioguanine