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PMID: 5762399 Published · ppublish English Journal Article

[Chloroplast ribosomes: stereospecificity of inhibition by chloramphenicol].

Science (New York, N.Y.) ·Vol. 163 ·No. 3866 ·1969-01-31 ·Pages 477-8

Ellis RJ

Abstract

Chloroplast ribosomes from tobacco leaves show the same stereospecificity of inhibition by chloramphenicol as bacterial ribosomes do. Cytoplasmic ribosomes from the same leaves are unaffected by chloramphenicol. These results remove doubts raised by nonstereospecific effects of chloramphenicol on higher plant cells and support the concept that chloroplasts have evolved from prokaryotes.

MeSH Terms
Carbon Isotopes Chloramphenicol/pharmacology Chloroplasts/drug effects,metabolism Cycloheximide/pharmacology Depression, Chemical Leucine/metabolism Plant Proteins/biosynthesis Plants, Toxic Ribosomes/drug effects,metabolism Solubility Stereoisomerism Surface-Active Agents Tobacco/cytology
Chemicals
Carbon Isotopes Plant Proteins Surface-Active Agents Chloramphenicol Cycloheximide Leucine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Ellis R J
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1969-01-31
Pages
477-8
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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