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PMID: 5778002 Published · ppublish English Journal Article

Glycosphingolipids with Lewis blood group activity: uptake by human erythrocytes.

Science (New York, N.Y.) ·Vol. 164 ·No. 3879 ·1969-05-02 ·Pages 553-5

Marcus DM, Cass LE

Abstract

The Lewis blood group antigens of the human erythrocyte are acquired from plasma and not synthesized in situ. Although assumed previously to be glycoproteins, tile Lewis antigens in plasma are glycosphingolipids Which are taken up by the the erythrocyte membrane from lipoproteins or from aqueous dispersions.

MeSH Terms
Blood Group Antigens Chromatography, Thin Layer Erythrocytes/immunology,metabolism Glycolipids/metabolism Glycoproteins Hemagglutination Inhibition Tests Humans Isoantigens/analysis Lewis Blood Group Antigens Lipoproteins/metabolism Saliva/immunology
Chemicals
Blood Group Antigens Glycolipids Glycoproteins Isoantigens Lewis Blood Group Antigens Lipoproteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Marcus D M
Cass L E
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.164.3879.553
Published
1969-05-02
Pages
553-5
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.164.3879.553 View journal details
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